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Published on: March 18, 2020
Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery
Lin-Lin Lan1, Qiu-Rong Yang1,2, Pei-Yun Zhuang1
1Department of Voice Medicine, Xiamen Key Laboratory of Voice Medicine, Zhongshan Hospital of Xiamen University, School of Medicine Xiamen University Xiamen China.
Summary
Optimal voice rest after phonomicrosurgery depends on surgical depth. Superficial lamina propria injuries heal best with 1 day of voice rest, while mid-deep lamina propria injuries benefit from 3 days for improved vocal function and healing.
Area of Science:
- Otolaryngology
- Regenerative Medicine
- Voice Science
Background:
- The optimal duration of voice rest following phonomicrosurgery is debated due to conflicting clinical findings.
- A controlled animal model for studying voice rest effects on vocal fold healing is lacking.
Purpose of the Study:
- To establish the optimal postoperative voice rest duration after phonomicrosurgery.
- To utilize a controlled rabbit model to investigate the impact of voice rest on vocal fold wound healing.
Main Methods:
- Developed distinct phonomicrosurgery injury models in rabbits: superficial lamina propria (SLP) and mid-deep lamina propria (MDLP).
- Assessed voice rest durations using ex vivo laryngeal phonatory vibration, histopathology (H&E, Alcian Blue, EVG), and texture analysis (GLCM).
Main Results:
- For SLP injuries, 1 day of voice rest yielded superior voice quality and histological organization.
- For MDLP injuries, 3 days of voice rest promoted optimal wound healing, better vocal function, improved vibration, and reduced fibrosis.
Conclusions:
- Postoperative voice rest duration should be tailored to the surgical depth.
- Differentiated voice rest protocols based on injury extent can optimize vocal fold healing and function.
