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Published on: December 20, 2024
Variations in the Severity of Rhinitis Symptoms: A Systematic Review and Meta-Analysis
Asher T Ripp1,2, Pranav A Patel1, Shaun A Nguyen1
1Department of Otolaryngology - Head and Neck Surgery Medical University of South Carolina Charleston South Carolina USA.
Summary
Nasal congestion is the most severe rhinitis symptom across all types. Allergic rhinitis and symptom duration significantly impact overall disease severity and individual symptom scores.
Area of Science:
- Allergy and Immunology
- Otolaryngology
- Clinical Medicine
Background:
- Rhinitis presents with key symptoms like nasal obstruction, rhinorrhea, sneezing, and itching.
- Varied presentations across rhinitis subtypes complicate diagnosis and categorization.
Purpose of the Study:
- To characterize the baseline presentation of rhinitis.
- To highlight differences in symptom presentation among rhinitis subtypes.
Main Methods:
- A meta-analysis of 89 studies (N=14,448 patients) was conducted.
- Data from PubMed, Scopus, and CINAHL were analyzed for baseline rhinitis symptoms.
- Total Nasal Symptom Score (TNSS) and Visual Analog Scale (VAS) were key outcome measures.
Main Results:
- Nasal congestion was the most severe symptom (2.03) across all rhinitis patients.
- Rhinorrhea was the most frequent moderate/severe symptom (93.2%).
- Allergic rhinitis (AR) patients reported higher overall TNSS and specific symptom scores compared to nonallergic rhinitis (NAR) patients, while NAR patients experienced more severe nasal congestion.
Conclusions:
- Nasal congestion is the predominant severe symptom in all rhinitis subtypes.
- Allergic status and symptom duration are critical factors influencing rhinitis severity and symptom profiles.
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