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Updated: Aug 5, 2026
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
The Impact of BMI on the Differences Between Drug-Induced Sleep Endoscopy and Müller Maneuver
Jun-Fang Xue1, Hong-Guang Guo1, Su-Jeong Lee1
1Department of Otorhinolaryngology Head and Neck Surgery Peking University International Hospital Beijing China.
Purpose:
To explore the differences in drug-induced sleep endoscopy (DISE) and Müller Maneuver (MM) results and study the impact of body mass index (BMI) on these differences.
Study Design:
Prospective observational study.
Methods:
Forty patients with OSAHS were included in this study. All enrolled patients were evaluated for MM and DISE using the Velum, Oropharynx lateral walls, Tongue Base, and Epiglottis (VOTE) classification to describe the type, site, and degree of upper airway collapse.
Results:
The differences between MM and DISE were statistically significant at the tongue base (p < 0.001) and epiglottis levels (p < 0.001). At the epiglottis level, the differences of identifying severe obstruction between DISE and MM were statistically significant in the BMI < 25 kg/m² (p = 0.033) and BMI 25-30 kg/m² groups (p = 0.049). But for the BMI ≥ 30 kg/m² group, the difference was not statistically significant (p = 0.077).
Conclusion:
DISE is more sensitive in detecting obstructions of OSAHS at the tongue base and epiglottis levels, especially in non-obese patients. MM could be a reasonable alternative in obese OSAHS patients when DISE is not available.
