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Updated: Aug 5, 2026

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
Heptanuclear iron complex as a potential contrast agent for MRI
Ekaterina E Batueva1,2, Alsu R Sharipova1, Olga A Turanova1
1Zavoisky Physical-Technical Institute, FRC Kazan Scientific Center, Russian Academy of Sciences, Sibirsky Tract, 10/7, Kazan, 420029, Russia.
Abstract:
A heptanuclear complex of the composition [Fe(II)(CN)6{Fe(III)](L)}6](SCN)2, where L = dianion N,N-bis(1-hydroxy-2-benzylidene)-1,7-diamino-4-azageptane has been studied as a potential contrast agent for magnetic resonance imaging. The longitudinal and transverse relaxation times of water in a colloidal solution of this molecular magnet with sodium dodecyl sulfate were measured by 1H nuclear magnetic resonance spectroscopy, depending on the concentration, and its relaxivity was calculated. The obtained relaxation values indicate that this complex is a promising candidate for use as a contrast agent in magnetic resonance imaging. This preliminary study is aimed at identifying the possibility of applying the heptanuclear complex as a magnetic resonance imaging contrast agent.
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