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Human GBP4 promotes TRIM21-BIP-dependent autophagy to restrict M. tuberculosis infection by preventing SORT1-mediated

Qinglong Guo1, Jing Bi1, Yu Fu1

  • 1National Clinical Research Center for Infectious Diseases, Guangdong Key Laboratory for Diagnosis & Treatment of Emerging Infectious Diseases, Shenzhen Key Laboratory for Infectious Diseases, Shenzhen Third People's Hospital, Southern University of Science and Technology, Shenzhen 518112, China.

Cell Reports
|July 25, 2026
PubMed

Keywords:
AKTBIPCP: microbiologyCP: molecular biologyGRNIFNsMycobacterium tuberculosisTRIM21autophagy fluxhuman GBP4lysosomal acidification

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