Related Experiment Video
Updated: Aug 6, 2026

A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
Patellofemoral Instability in Children with Down Syndrome
Robert G Yoder1, Paraskevi M Limberatos2, Joseph A Magoline3
1Department of Orthopaedic Surgery, Cleveland Clinic Akron General, Akron, OH, USA.
None:
The incidence of patellofemoral instability (PFI) in patients with Down syndrome (DS) is 10% to 20%. Treatment of PFI in this cohort has evolved over the past four decades. Nonoperative management largely prevails today; however symptomatic patients with DS and recurrent instability may benefit from patellar stabilization surgery. Combined, physeal-sparing soft tissue procedures have become the focus of modern-day surgeons when operative intervention is pursued in skeletally immature patients. This review article outlines the seldom-discussed topic of PFI in patients with DS and highlights the need for high-quality, outcome-based research on the optimal management in this specific cohort.
Key Concepts:
(1)Asymptomatic patients with Down syndrome (DS) and patellofemoral instability (PFI) are treated nonoperatively.(2)Surgical treatment of PFI has evolved and may benefit patients with DS and symptomatic PFI.(3)Approximately 20% of patients with DS develop PFI. Reported recurrence rates following surgical intervention range from 0% to 20%.(4)High-quality, outcome-based research in this population is needed.
Related Concept Videos
Bones of the Lower Limb: Femur and Patella
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...