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Updated: Aug 6, 2026

Performing Repeated Intraoperative Impedance Telemetry Measurements during Cochlear Implantation
Published on: August 4, 2023
Cochlear implants are associated with reduced cognitive decline risk: A 20-year cohort study
Filippos Anagnostakis1,2, Michail Kokkorakis3,4, Ilias Papadimopoulos5
1Artificial Intelligence in Biomedical Imaging Laboratory (AIBIL), Center for AI and Data Science for Integrated Diagnostics (AI2D), Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.
Introduction:
We investigated the association between cochlear implantation and the risk of cognitive decline in adults with hearing loss using a national population cohort.
Methods:
Our cohort comprised 4106 participants who underwent cochlear implantation and matched controls with untreated hearing loss, followed over a median of 7.3 years. Propensity score matching was applied to control for confounders, and Kaplan-Meier analysis was used to assess time-to-event outcomes.
Results:
Participants with cochlear implants had a significantly reduced risk of all-cause dementia (hazard ratio [HR] 0.61, 95% confidence interval [CI] 0.50-0.74), mild cognitive impairment (HR 0.53, 95% CI 0.40-0.70), and memory loss (HR 0.54, 95% CI 0.45-0.65) compared with controls. These associations remained significant in sex-stratified analyses for both male and female participants.
Discussion:
These results support early auditory intervention as a dementia prevention strategy and warrant further research with longer follow-up periods across diverse populations.