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Updated: Aug 5, 2026
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A High-throughput Assay for the Prediction of Chemical Toxicity by Automated Phenotypic Profiling of Caenorhabditis elegans
Published on: March 14, 2019
Caenorhabditis elegans as an Alternative Model in Pharmacological and Toxicological Studies Involving Microplastics
Pedro Henrique Macedo Moura1, Maria Eduarda de Britto Sá2, José Claudson Gomes Amorim2
1Postgraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Abstract
None:
The model organism Caenorhabditis elegans possesses genes and signaling pathways homologous to those of humans and mammals. Thus, this organism can contribute to research on the acute, chronic, and transgenerational toxicological effects of microplastics on systems such as the locomotor, neuronal, and reproductive systems.
