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Case Report: Rare Peripheral Neuropathy With Abdominal Wall Allodynia in Extensive-Stage Small-Cell Lung Cancer
Ruidan Li1, Zhen Li2, Xiaoqian Zhai3
1Respiratory and Critical Care Medicine Department, Norinco General Hospital, Xi'an, Shaanxi, China.
Thoracic Cancer
|July 26, 2026
Summary
Immune checkpoint inhibitors (ICIs) can cause rare side effects like peripheral neuropathy in extensive-stage small-cell lung cancer patients. Early identification and treatment of these immune-related adverse events (irAEs) are crucial for patient outcomes.
Area of Science:
- Oncology
- Immunology
- Neurology
Background:
- Immune checkpoint inhibitors (ICIs) like PD-1/PD-L1 inhibitors are standard for extensive-stage small-cell lung cancer (ES-SCLC).
- Increased use of immunotherapy has led to more reported immune-related adverse events (irAEs).
- Identifying atypical irAEs requires significant clinical experience.