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Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Sabine Irtan1, Michael Abele2, Calogero Virgone3,4
1Department of Pediatric Visceral and Neonatal Surgery, Sorbonne University, Armand Trousseau Hospital - Assistance Publique Hôpitaux de Paris, Paris, France.
Abstract:
Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low-grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved. This manuscript presents harmonized recommendations for the diagnosis, treatment, and long-term management of pediatric SPN established by the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) in collaboration with the European Reference Network for Pediatric Oncology (ERN PaedCan) after careful review of the literature and experts' opinions refined by selected external reviewers.