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Pediatric Renal Osteodystrophy: A Bibliometric Analysis of Global Research Trends and Emerging Themes

Trayi Yada1, Pranay Gadikota2, Latha Ganti3

  • 1Providence Day School.

Orthopedic Reviews
|July 27, 2026
PubMed

Insights

Pediatric renal osteodystrophy research has evolved significantly, shifting focus from bone issues to chronic kidney disease-mineral bone disorder. Future studies should address nutrition and global health disparities.

Area of Science:

  • Nephrology
  • Pediatrics
  • Bone Biology

Background:

  • Pediatric Renal Osteodystrophy (pROD) is a serious complication of chronic kidney disease in children.
  • It leads to bone growth impairment, pain, deformities, fractures, and reduced quality of life.

Purpose of the Study:

  • To analyze global research trends, key contributors, collaborations, and emerging topics in pediatric renal osteodystrophy.
  • To provide a bibliometric overview of the field's evolution.

Main Methods:

  • Bibliometric analysis of 768 papers from 1971-2026 (Web of Science).
  • Utilized VOSviewer for assessing publication quantity, author/journal metrics, subject categories, co-authorship, keyword co-occurrences, and co-citations.

Main Results:

  • Research output increased significantly post-2005, peaking in 2013 and 2020.
  • Urology & Nephrology and Pediatrics were dominant fields; Salusky IB was the most prolific author; Pediatric Nephrology was the top journal.
  • Research evolved from bone histology to CKD-mineral bone disorder (CKD-MBD), mineral metabolism, FGF-23, and therapeutic interventions.

Conclusions:

  • Pediatric renal osteodystrophy research has advanced from skeletal concerns to encompass CKD-MBD.
  • Future research should focus on nutrition, post-transplant bone issues, and underserved global populations.
Abstract

Keywords:
bibliometric analysispediatric osteodystrophy

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