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Contrast-induced sialadenitis mimicking iodinated contrast allergy in a patient with acute myelogenous leukemia: A

Andrew Zhu1,2, Leon Lin Chen1,3, Dona Bugov4

  • 1Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

Journal of the American Association of Nurse Practitioners
|July 27, 2026
PubMed

Iodinated contrast-enhanced imaging is a well-established and ubiquitous diagnostic tool that offers many benefits in oncology care. However, such benefits are accompanied by risks such as nephrotoxicity. The below report describes a 71-year-old woman with acute myelogenous leukemia who developed iodine contrast-induced sialadenitis, manifested by acute neck swelling and gland tenderness, within a day after undergoing imaging for infectious workup at a tertiary oncology center. Despite the adverse event, the patient proved to have a patent airway and was discharged home after overnight monitoring in the intensive care unit. The patient's rare complication highlights the multitude of risks that can accompany iodine contrast administration and emphasizes the necessity of exercising due caution before using contrast-enhanced imaging.

Keywords:
Acute care nurse practitionercancercritical careiodine contrast

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