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Family-Centered Child Obesity Treatment: The TEAM UP Randomized Clinical Trial
Amanda E Staiano1, Stephen R Cook2, Richard I Stein3
1Pennington Biomedical Research Center, Baton Rouge, Louisiana.
JAMA Pediatrics
|July 27, 2026
Summary
Enhanced standard of care with family-based behavioral treatment (ESOC+FBT) significantly reduced pediatric obesity more than ESOC alone. This approach is feasible for diverse populations, improving quality of life.
Area of Science:
- Pediatric Obesity Management
- Comparative Effectiveness Research
- Behavioral Health Interventions
Background:
- Limited access to pediatric weight management services impacts families.
- Childhood obesity is a significant public health concern requiring effective interventions.
- Primary care settings offer a potential venue for obesity treatment delivery.
Purpose of the Study:
- To compare the effectiveness of enhanced standard of care with family-based behavioral treatment (ESOC+FBT) versus ESOC alone in reducing relative weight in children and adolescents.
- To evaluate the impact of ESOC+FBT on children's quality of life.
- To assess the feasibility of ESOC+FBT in diverse primary care settings.
Main Methods:
- Pragmatic, comparative-effectiveness randomized clinical trial involving 730 children aged 6-15 with obesity.
- Interventions included ESOC (PCP-led) and ESOC+FBT (additional behavioral intervention).
- Primary outcome was change in percent median BMI at 12 months; quality of life was also assessed.
Main Results:
- ESOC+FBT resulted in a significantly greater reduction in percent median BMI (-6.4%) compared to ESOC alone (-2.6%).
- Between-group difference in BMI reduction was -3.8 units (P=.002).
- Both groups showed improved quality of life, with greater gains in the ESOC+FBT group.
Conclusions:
- ESOC+FBT is more effective than ESOC alone in reducing pediatric obesity.
- Integrating FBT into primary care is valuable and feasible across diverse populations.
- This approach shows promise for improving health outcomes and quality of life for children with obesity.
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