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Streptococcus dysgalactiae subsp. equisimilis in paediatric febrile pharyngitis: A case series with molecular
Marianneta Chatzopoulou1, Stylianos Karapashis1, Elizabeth Barbara Tatsi2
1Medical Microbiology Department, General Hospital of Larissa, Greece.
Insights
Six children in Greece experienced pharyngitis due to Streptococcus dysgalactiae subsp. equisimilis. This pathogen, distinct from Streptococcus pyogenes, showed varied antibiotic resistance, highlighting the need for better surveillance of this infection.
Area of Science:
- Pediatric Infectious Diseases
- Bacteriology
- Public Health Microbiology
Background:
- Pharyngitis is a common pediatric illness.
- Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of pharyngitis.
- Limited regional data exists on SDSE pediatric infections.
Abstract:
We report six paediatric cases of pharyngitis caused by Streptococcus dysgalactiae subsp. equisimilis presenting to a Greek public hospital over one year. All children had fever and cervical lymphadenopathy and tested negative for Streptococcus pyogenes. All cases came from a common socioeconomically disadvantaged, high-density setting; however, molecular typing detected two types, stG4 and stC36. All isolates were susceptible to beta-lactams, vancomycin, linezolid and co-trimoxazole. Resistance to macrolides and lincosamides was detected in three isolates and one was resistant to tetracycline. Given the increasing global incidence of this pathogen, this report provides regional data and underscores the need for improved surveillance.
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