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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Small molecule ligands for the melanocortin-4 receptor: pharmacology, biased signaling, and pharmacoperone potential

Ya-Xiong Tao1, Ren-Lei Ji1

  • 1Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, 36849, USA.

Molecular and Cellular Endocrinology
|July 27, 2026
PubMed

Keywords:
Biased signalingCachexiaInverse agonistMelanocortin-4 receptorObesityPharmacoperoneSmall molecule

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