Related Experiment Video
Updated: Aug 5, 2026

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Retrograde CTO PCI via Epicardial Collaterals: Techniques, Tools, and Risk Mitigation
Paola Scarparo1, Pierfrancesco Agostoni2, Omer Goktekin3
1Department of Interventional Cardiology, Thoraxcenter, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Retrograde percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) using epicardial collaterals is a complex but viable alternative. Innovations enhance safety and feasibility, enabling revascularization in challenging cases.
Area of Science:
- Interventional Cardiology
- Vascular Surgery
Background:
- Retrograde percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) is a complex procedure.
- Septal collaterals are preferred for safety due to their intramuscular course.
- Epicardial collaterals offer an alternative when septal routes are not feasible.
Purpose of the Study:
- To provide practical guidance on retrograde CTO PCI via epicardial collaterals.
- To outline current devices and techniques for this challenging procedure.
- To offer recommendations for complication prevention and management.
Main Methods:
- Review of current literature and techniques for retrograde CTO PCI.
- Focus on the use of epicardial collateral pathways.
- Discussion of specialized devices like microcatheters and guidewires.
Main Results:
- Innovations in devices have improved the safety and technical feasibility of epicardial CTO PCI.
- Retrograde CTO PCI via epicardial collaterals is a valuable option for complex anatomies.
- Experienced operators can achieve successful revascularization using this approach.
Conclusions:
- Epicardial collaterals are an important alternative for retrograde CTO PCI when other routes fail.
- Advanced devices and techniques enhance safety and success rates.
- This strategy allows complete revascularization in challenging CTO cases.
Related Concept Videos
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization I: Pre-Procedure Overview
Coronary Artery Disease V: Interprofessional Care
