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Upregulation of Somatostatin Receptor Expression in Lactating Breast Shown in 99mTc-HYNIC-TOC Scintigraphy
Mengyao Jia1, Jie Feng1, Yaping Luo1
1Department of Nuclear Medicine, State Key Laboratory of Common Mechanism Research for Major Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, China.
Abstract:
A 31-year-old female patient with a 4-year history of multiple endocrine neoplasia type 1 (MEN1) presented with abdominal pain and weight loss that she had been experiencing over the past 6 months. Somatostatin receptor (SSTR) scintigraphy using 99mTc-HYNIC-TOC revealed increased uptake in the known pancreatic neuroendocrine tumor as well as diffuse increased uptake in bilateral lactating breasts. This case highlights physiological upregulation of somatostatin receptor expression in a lactating breast.
