Related Experiment Video
Updated: Aug 5, 2026
10:09
Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging
Published on: September 12, 2012
Mapping the Global Trajectory and Key Trends of Temporal Interference Stimulation
Li Qi1,2, Zhishun Gao1, Xiaomin Pan1
1Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Bioengineering (Basel, Switzerland)
|July 28, 2026
Summary
Temporal interference stimulation (TIS) is a novel neuromodulation technique. Research shows TIS is rapidly advancing from basic science toward clinical applications, requiring further optimization for therapeutic use.
Area of Science:
- Neuromodulation
- Biophysics
- Neuroscience
Background:
- Temporal interference stimulation (TIS) emerged in 2017 as a promising non-invasive neuromodulation method.
- TIS offers potential for targeting deep brain structures, necessitating a review of its research evolution.
Purpose of the Study:
- To systematically map the scientific landscape of TIS research using bibliometric methods.
- To characterize the knowledge structure, core themes, and emerging frontiers in TIS development.
Main Methods:
- Bibliometric analysis of TIS research publications.
- Systematic mapping of the scientific field's trajectory and thematic evolution.
Main Results:
- TIS research has rapidly expanded from animal studies and biophysical validation to computational modeling and human applications.
- Current focus includes cross-species scaling, dosimetry, comparative analysis, targeting, and risk assessment (e.g., conduction block).
Conclusions:
- TIS is evolving into a complex neuromodulation tool with therapeutic potential.
- Overcoming engineering and translational barriers via individualized modeling and human studies is crucial for clinical adoption.