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Cross-Domain Robust Pruning for Polyp Segmentation: Multi-Encoder Feature Fusion Beats Single-Encoder Baselines
Chia-Pei Tang1,2, Hong-Yi Chang3, Tzu-Shan Chang4
1Division of Gastroenterology, Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi City 622401, Taiwan.
Bioengineering (Basel, Switzerland)
|July 28, 2026
Summary
Fusing diverse image encoders improves training-free dataset pruning for medical image segmentation, enhancing robustness across different polyp datasets. This method, Multi-Encoder Diverse Pruning (MEDP), outperforms random sampling and manual approaches.
Area of Science:
- Computer Vision
- Medical Imaging
- Machine Learning
Background:
- Medical image segmentation demands extensive pixel-level annotations, increasing dataset construction costs.
- Data-efficient training methods are crucial for developing robust segmentation models.
Purpose of the Study:
- To evaluate if fusing complementary pretrained image encoders enhances training-free dataset pruning robustness.
- To quantify the robustness of this approach across heterogeneous polyp segmentation domains.
Main Methods:
- Propose Multi-Encoder Diverse Pruning (MEDP), a training-free method fusing ResNet-18 and DINOv2 ViT-S/14 features.
- Utilize Louvain modularity maximization for training pool partitioning and Maximal-Marginal Relevance (MMR) for sample selection.
- Benchmark MEDP against 12 baselines at a 20% retention ratio across Kvasir-SEG, CVC-ClinicDB, and a combined cross-domain pool.
Main Results:
- MEDP achieved the highest mean test Dice score of 0.7324 on the challenging Combined cross-domain pool.
- MEDP significantly outperformed uniform random sampling (Cohen's d = +1.79, p = 0.002).
- Hand-crafted structure-aware methods failed to outperform uniform random sampling.
Conclusions:
- Combining multi-encoder features with MMR diversity offers a robust and effective strategy for medical imaging segmentation.
- The choice of pretrained image encoder is a critical factor in segmentation-aware pruning.
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