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Development of 3-decen-2-one/HP-β-CD Inclusion Complex with Enhanced Stability and Its Application for Potato
Xia Ge1, Yiwen Xu1, Zheng Huang2
1Institute of Agricultural Products Storage and Processing, Gansu Academy of Agricultural Sciences, Lanzhou 730070, China.
Abstract:
3-Decen-2-one is a promising natural potato sprout suppressant, but its high volatility, poor stability and low water solubility severely restrict its practical application. To overcome these drawbacks, a 3-decen-2-one/hydroxypropyl-β-cyclodextrin (HP-β-CD) inclusion complex with a 1:1 host-guest molar ratio was successfully prepared via the co-evaporation method, and the stability constant was calculated to be 596.43 M-1 by phase solubility studies. Molecular modeling demonstrated that the inclusion complex was primarily stabilized by van der Waals interactions, and the optimal binding conformation was that the alkyl chain of 3-decen-2-one inserted into the cavity from the wider rim of HP-β-CD. The inclusion complex was further characterized by 1H NMR, FT-IR, TG, and SEM. 3-Decen-2-one showed a better water solubility, thermal stability and release properties after complexation. In the potato storage evaluation, the complex exhibited greater sprout inhibition than free 3-decen-2-one; effectively reduced weight loss, the respiration rate, and MDA accumulation; and maintained a higher Vc and lower reducing sugar levels. Therefore, the obtained inclusion complex is a promising approach to stabilize and achieve the sustained release of 3-decen-2-one as a natural sprout inhibitor for potato storage.
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