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Biomarkers of Inflammaging and Cellular Senescence in Musculoskeletal (MSK) Diseases: The Knowns and the Unknowns

Payal Ganguly1,2

  • 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds LS7 4SA, UK.

Biomedicines
|July 28, 2026
PubMed

Insights

As people age, age-related diseases (ARDs) increase, impacting quality of life. This review explores biomarkers for musculoskeletal (MSK) ARDs to promote healthy aging and longevity.

Area of Science:

  • Gerontology and Musculoskeletal Health

Background:

  • Advancing age is linked to increased age-related diseases (ARDs), significantly impacting the quality of life (QOL) in the elderly.
  • Musculoskeletal (MSK) diseases are a major global health burden associated with aging, cellular senescence, inflammaging, and immunosenescence.
Keywords:
anti-agingbiomarkersbone aginghealthy agingimmunosenescenceinflammaginglongevitymusculoskeletal (MSK)senescence

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