Related Experiment Video

Updated: Aug 5, 2026

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas
04:41

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

Published on: July 25, 2025

Linagliptin, a Selective DPP-4 Inhibitor, Attenuates Ketamine- and Diazepam-Induced Deficits in Passive Avoidance

Krzysztof Fronc1, Piotr Listos2, Paulina Kasprzak3

  • 1Department of Pharmacology and Pharmacodynamics, Medical University of Lublin, Chodźki 4a St., 20-093 Lublin, Poland.

Brain Sciences
|July 28, 2026
PubMed
Summary

Linagliptin, a type 2 diabetes drug, improved memory performance in mice by increasing brain-derived neurotrophic factor (BDNF) in the prefrontal cortex. This suggests potential benefits for central nervous system function beyond diabetes management.

Keywords:
BDNFELISAGLP-1 peptidediazepamketaminememory impairmentspassive avoidance test

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