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The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Dry Socket After Mandibular Third Molar Extraction: Incidence and Risk Factors in a Single-Surgeon Retrospective
Takahiro Yamashiro1,2, Yoichiro Ogino3, Tomohiro Yamada4
1Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan.
Healthcare (Basel, Switzerland)
|July 28, 2026
Summary
Female patients, older age (≥30 years), and oral contraceptive use are significant risk factors for dry socket after mandibular third molar extraction. These patient-related factors influence healing capacity and contribute to postoperative complications.
Area of Science:
- Oral and Maxillofacial Surgery
- Dental Research
- Postoperative Complication Analysis
Background:
- Dry socket (alveolar osteitis) is a common complication following mandibular third molar extraction.
- Understanding incidence and risk factors is crucial for effective prevention and patient management.
Purpose of the Study:
- To investigate the incidence and identify independent risk factors for dry socket after mandibular third molar extraction.
- To analyze patient-demographic and surgical variables associated with dry socket development.
Main Methods:
- Retrospective analysis of 3033 mandibular third molar extractions from 2384 patients (June 2020 - March 2024).
- Clinical data and panoramic radiographs assessed for angulation, depth, and gingival coverage.
- Statistical analysis including chi-square, Fisher's exact tests, and multivariate logistic regression to determine risk factors.
Main Results:
- Overall dry socket incidence was 2.6% (80 cases).
- Significantly higher incidence in females (3.3%) vs. males (1.4%) (p < 0.01).
- Increased risk associated with age ≥ 30 years and oral contraceptive use (p < 0.01).
Conclusions:
- Female sex, age ≥ 30 years, and oral contraceptive use are significant independent risk factors for dry socket.
- Patient-related factors impacting healing capacity play a key role in dry socket development.
- Identifying high-risk patients enables targeted preventive strategies to reduce postoperative complications.