Related Experiment Video
Updated: Aug 5, 2026
12:16
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
Published on: October 16, 2018
From Cure to Combat: Deployment After Lymphoma
Kyle Yuan1, Johnathon M Rolwes2, Sarah Darmon3,4
1Department of Hematology/Oncology, Walter Reed National Military Medical Center, Bethesda, MD 20814, USA.
Journal of Clinical Medicine
|July 28, 2026
Summary
Approximately 13.7% of previously deployed active-duty service members diagnosed with lymphoma deployed again after treatment. Hodgkin lymphoma survivors were more likely to redeploy, demonstrating successful cancer survivorship in military personnel.
Area of Science:
- Oncology
- Military Medicine
- Hematologic Malignancies
Background:
- Lymphoma is the most common hematologic malignancy among active-duty service members (ADSMs).
- Fitness for duty post-lymphoma diagnosis impacts careers and military readiness.
- Previous studies lack data on redeployment after lymphoma treatment in ADSMs.
Purpose of the Study:
- To determine the proportion of previously deployed ADSMs who redeployed after a lymphoma diagnosis.
- To characterize the deployments of these service members.
Main Methods:
- Retrospective analysis of lymphoma cases (Hodgkin lymphoma [HL] and non-Hodgkin lymphoma [NHL]) diagnosed between 2001-2022 from the Defense Health Agency Cancer Registry.
- Deployment data sourced from the Defense Manpower Data Center.
- Analysis included only ADSMs with a history of deployment at the time of diagnosis.
Main Results:
- A total of 866 previously deployed ADSMs with lymphoma were identified (455 HL, 411 NHL).
- 119 individuals (13.7%) deployed post-diagnosis: 18.9% with HL and 8.0% with NHL (p < 0.001).
- The mean interval to redeployment was 5.1 years for HL and 4.5 years for NHL; all 119 individuals were alive at last follow-up.
Conclusions:
- Roughly one in six previously deployed ADSMs with lymphoma redeployed after diagnosis and treatment, typically within five years.
- Deployment after lymphoma treatment is feasible for a significant number of service members.
- These findings underscore the effectiveness of military cancer care and its positive impact on operational readiness.
Related Concept Videos
02:56Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
02:56Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:49Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:16Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...