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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

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Published on: October 20, 2017

Endovascular Therapy Versus Open Surgery for Common Femoral Artery Atherosclerotic Occlusive Disease: A Systematic

Chuwen Chen1, Yiyuan Li1, Jing Hu2

  • 1Division of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

Journal of Clinical Medicine
|July 28, 2026
PubMed

Insights

Endovascular therapy (EVT) for common femoral artery disease reduces early complications and hospital stays compared to open surgery (OS). However, open surgery offers more durable patency and fewer reinterventions, necessitating individualized treatment strategies.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Cardiovascular Disease

Background:

  • Optimal revascularization for common femoral artery (CFA) atherosclerotic occlusive disease is debated.
  • Comparing endovascular therapy (EVT) and open surgery (OS) is crucial for treatment decisions.

Purpose of the Study:

  • To systematically review and meta-analyze perioperative and long-term outcomes of EVT versus OS for CFA atherosclerotic occlusive disease.
  • To compare key clinical endpoints including morbidity, patency, reintervention, and survival.

Main Methods:

  • Systematic review and meta-analysis of comparative studies.
  • Searched PubMed, Embase, Web of Science, Cochrane Library, and ClinicalTrials.gov.
  • Pooled time-to-event data as hazard ratios (HRs) and assessed risk of bias and evidence certainty.

Main Results:

  • EVT reduced 30-day morbidity, wound complications, and hospital stay compared to OS.
  • EVT increased distal embolization and follow-up major amputation rates.
  • OS demonstrated more durable patency and lower reintervention rates, though amputation-free survival was similar.

Conclusions:

  • EVT offers advantages in early recovery and reduced complications.
  • OS provides superior long-term patency and fewer reinterventions.
  • Individualized treatment is recommended due to heterogeneous and observational evidence.

Keywords:
atherosclerotic occlusivecommon femoral arteryendovascular therapymeta-analysisopen surgeryperipheral arterial disease

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