Clinical and Surgical Risk Factors for Wound Healing Disorders Following Non-Instrumented Lumbar Spine Surgery Using...

Area of Science:

• Spine Surgery
• Wound Healing
• Surgical Outcomes

Background:

• Wound healing disorders (WHDs) are a complication following lumbar spine surgery.
• Identifying risk factors for WHDs in non-instrumented procedures is crucial for patient care.
• Previous studies may not have specifically focused on non-instrumented lumbar spine surgery.

Purpose of the Study:

• To identify clinical and laboratory factors associated with WHDs in non-instrumented lumbar spine surgery.
• To utilize penalized regression analysis for robust variable selection.
• To determine independent predictors of postoperative WHDs.

Main Methods:

• Retrospective cohort study of 1269 adult patients undergoing non-instrumented lumbar spine surgery (2015-2023).
• Primary outcome: postoperative WHD requiring intervention.
• Penalized regression analysis (LASSO and Firth-corrected logistic regression) for variable selection and modeling.

Main Results:

• Wound healing disorders (WHDs) occurred in 2.7% of patients.
• Older age and longer operative duration were significantly associated with WHDs (p < 0.001).
• Advanced age (OR 1.03) and operative duration (OR 1.01) were independently associated with WHDs in the final model.

Conclusions:

• Wound healing disorders after non-instrumented lumbar spine surgery are multifactorial.
• Advanced age and prolonged operative time are independent risk factors for WHDs.
• The findings aid in risk stratification and prevention strategies for WHDs.