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Gestational-Age Clustering of Recurrent Placental Abruption: A Multicenter Retrospective Descriptive Study
Mako Nakamura1, Kaori Iino1, Takashi Ozaki2
1Department of Obstetrics and Gynecology, Graduate School of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.
Journal of Clinical Medicine
|July 28, 2026
Summary
Recurrent placental abruption often occurs near the same gestational age as the previous event. This finding in multiparous women suggests timing may be key for future surveillance strategies.
Area of Science:
- Perinatal Medicine
- Obstetrics
- Reproductive Health
Background:
- Placental abruption recurrence risk is high, but timing is poorly understood.
- Understanding recurrence timing aids in managing future pregnancies.
Purpose of the Study:
- To describe the gestational age distribution of recurrent placental abruption.
- To compare recurrent vs. first-time placental abruption in multiparous women.
Main Methods:
- Retrospective, multicenter descriptive study (2003-2024).
- Included 239 placental abruption cases from nine Japanese perinatal centers.
- Compared clinical characteristics and outcomes between recurrent (n=10) and first-time (n=134) abruption cases.
Main Results:
- Recurrent placental abruption often occurred within ±1-2 weeks of the previous episode's gestational age (6/11 within ±1 week, 8/11 within ±2 weeks).
- Maternal age was higher in the recurrent group; other factors like BMI and hypertensive disorders were similar.
- Most clinical features and outcomes did not differ significantly, except for higher birth weight in the recurrent group.
Conclusions:
- Recurrent placental abruption shows a tendency for similar gestational age timing.
- Findings may help individualize surveillance but require confirmation in larger studies.
- Further research is needed to validate these exploratory findings.
