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The action of certain antibiotics and ether on swine enzootic pneumonia
Abstract:
The susceptibility of Mycoplasma hyopneumoniae to the action of three antibiotics and diethyl ether was determined. Infected swine were used in an in vivo sensitivity detection system. The parameter of susceptibility was lesion prophylaxis. In vivo, Mycoplasma hyopneumoniae appeared to be resistant to diethyl ether, tylosin tartrate, and erythromycin, but was susceptible to the action of chlortetracycline. Chlortetracycline was effective in preventing the development of lesions when given at levels which would be practical in commercial swine operations.
Insights
Mycoplasma hyopneumoniae showed resistance to tylosin tartrate, erythromycin, and diethyl ether. However, chlortetracycline effectively prevented lesions in infected swine, offering a practical treatment option for producers.
Area of Science:
- Veterinary Microbiology
- Swine Infectious Diseases
- Antimicrobial Susceptibility Testing
Background:
- Mycoplasma hyopneumoniae is a primary cause of swine respiratory disease.
- Effective antimicrobial strategies are crucial for managing economic losses in swine production.
Purpose of the Study:
- To evaluate the in vivo efficacy of chlortetracycline, tylosin tartrate, erythromycin, and diethyl ether against Mycoplasma hyopneumoniae.
Main Methods:
- An in vivo sensitivity system using infected swine was employed.
- Lesion prophylaxis served as the primary indicator of antimicrobial susceptibility.
Main Results:
- Mycoplasma hyopneumoniae demonstrated resistance to diethyl ether, tylosin tartrate, and erythromycin in vivo.
- Chlortetracycline exhibited significant susceptibility, effectively preventing lesion development.
Conclusions:
- Chlortetracycline is a viable and practical option for controlling Mycoplasma hyopneumoniae-induced lesions in commercial swine.
- Antimicrobial resistance patterns necessitate careful selection of treatments for swine respiratory disease.