Green Synthesis of Silver Nanoparticles from Aloe vera: Antibacterial Potential Against Cyanobacteria from an Andean...

This work describes an efficient and environmentally friendly method for the synthesis of silver-based nanostructures through a green route using Aloe vera extract as a reducing agent, silver nitrate (AgNO₃) as a precursor, and polyvinylpyrrolidone (PVP, 10 kDa molecular weight) as a stabilizing agent. The formation of these structures was supported by UV-Vis spectroscopy, where a surface plasmon resonance (SPR) band was observed between 425 and 460 nm. Scanning electron microscopy revealed predominantly spherical features in the 300-500 nm range; however, the distinction between primary nanoparticles and aggregates cannot be conclusively established from SEM alone. EDX analysis indicated a silver content of 59.96 wt%. Antibacterial assays performed in Z8 medium demonstrated a reduction in cyanobacterial growth with increasing dosage, with complete inhibition observed at ≥20 μL (nominal MIC = 1.77 mg mL^-1, based on precursor estimation). Total dissolved solids and absorbance measurements exhibited a decreasing trend with increasing concentration (effect size = 0.87, p<0.001), supporting an inhibitory effect under the tested conditions. These findings suggest potential antibacterial activity. However, this study should be considered exploratory, and further work is required to elucidate the underlying mechanisms.