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Return-To-Work and Working Status After Surgery for Gastric and Esophageal Cancer: A Prospective Observational Study
Kentaro Goto1, Shigeo Hisamori1, Kohei Ueno1
1Department of Surgery Kyoto University Kyoto Japan.
Annals of Gastroenterological Surgery
|July 28, 2026
Summary
Most gastric and esophageal cancer survivors return to work within 18 months. Postoperative symptoms like appetite loss and weight loss significantly impact long-term work participation.
Area of Science:
- Oncology
- Surgical Outcomes
- Survivorship Research
Background:
- Improving survival rates in gastric and esophageal cancer necessitates focus on long-term survivorship outcomes.
- Sustained work participation is a critical aspect of quality of life for cancer survivors.
Purpose of the Study:
- To determine return-to-work (RTW) rates at 18 months post-curative surgery for gastric and esophageal cancers.
- To identify clinical and socioeconomic factors influencing delayed or failed RTW.
Main Methods:
- A multicenter, prospective cohort study of working-age Japanese patients undergoing curative surgery for gastric or esophageal cancer.
- Assessment of working status preoperatively and at 6, 12, and 18 months postoperatively.
- Exploratory analysis of patient-reported outcomes (QLQ-C30) and weight loss at 6 months.
Main Results:
- 124 of 158 (78.5%) patients were working at 18 months.
- Older age (≥65 years) and advanced pathological stage (≥III) were linked to non-working status.
- Postoperative appetite loss, financial difficulties, and significant weight loss (≥10%) at 6 months were associated with not working.
Conclusions:
- Nearly 80% of patients resume work 18 months after surgery.
- Postoperative nutritional status and symptom burden are key factors affecting long-term work participation.
- Identifying at-risk patients early can aid in supporting their return to work.
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