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Refractory urticarial dermatitis successfully treated with mycophenolate mofetil
Hugo J Leme1, Marcelo Pacheco Silva1, Adelina Costin1
1Dermatology Department, Unidade Local de Saúde de Almada-Seixal, Av. Torrado da Silva, 2805-267, Almada, Portugal.
Abstract:
Urticarial dermatitis is an uncommon inflammatory dermatosis characterized by persistent pruritic urticarial and eczematous eruptions associated with a dermal hypersensitivity reaction pattern on histopathology. We report a case of severe refractory urticarial dermatitis resistant to multiple therapies, including corticosteroids, cyclosporine, methotrexate, dapsone and azathioprine, which demonstrated significant clinical improvement following treatment with mycophenolate mofetil. This case highlights the diagnostic challenges of urticarial dermatitis and supports mycophenolate mofetil as a potential therapeutic option in refractory disease.
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