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Precision cardiovascular medicine: global imperative for equity through innovation
Jose R Medina-Inojosa1,2,3,4, Fatima Rodriguez5,6, Francisco Lopez-Jimenez4
1Division of Cardiology, Emory Clinical Cardiovascular Research Institute, Atlanta, GA, United States.
Frontiers in Cardiovascular Medicine
|July 28, 2026
Summary
Precision cardiovascular medicine offers new hope for preventing and managing heart disease globally. However, ensuring equitable access through inclusive policies is crucial to avoid widening health disparities.
Area of Science:
- Cardiovascular Medicine
- Health Equity
- Digital Health
Background:
- Cardiovascular disease is the leading global cause of mortality, disproportionately affecting low- and middle-income countries.
- Precision medicine, including AI, multiomics, and digital diagnostics, presents opportunities for cardiovascular disease prevention and management.
- Current innovations risk exacerbating health disparities without equity-centered policies.
Purpose of the Study:
- To propose a framework for equitable implementation of precision cardiovascular medicine.
- To outline strategies and policy levers for translating scientific advancements into population-level impact.
- To advocate for innovation as a public good and equity as a universal right in cardiovascular care.
Main Methods:
- The World Heart Federation (WHF) framework operationalizes equity through initiatives like the World Heart Observatory, Digital Health Roadmap, and Emerging Leaders Program.
- Focus on governance, workforce development, and care delivery to ensure inclusivity.
- Utilizing case studies from Africa, Latin America, and South/Southeast Asia to inform implementation strategies.
Main Results:
- The WHF framework provides a model for integrating equity into precision cardiovascular medicine.
- Identified implementation strategies and policy levers for global application.
- Highlighted the importance of regional exemplars in achieving population-level impact.
Conclusions:
- Precision cardiovascular medicine holds immense potential but requires an equity-first approach.
- Equity must be integrated from the inception of precision medicine initiatives.
- Achieving equitable outcomes necessitates a global commitment to innovation as a public good and equity as a universal right.
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