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Updated: Aug 5, 2026

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
06:22

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)

Published on: April 7, 2021

Acute Respiratory Distress Syndrome: Mechanical Ventilation vs. High-Frequency Percussive Ventilation

Daniel Sagan1,2, Carol Parise3, Imran Mohammed2,4

  • 1Department of Cardiopulmonary Sciences, School of Allied Health Professions, Loma Linda University Health, Loma Linda, California, USA, lluh.org.

Canadian Respiratory Journal
|July 28, 2026
PubMed
Summary

High-frequency percussive ventilation (HFPV) improves gas exchange in severe acute respiratory distress syndrome (ARDS) when conventional methods fail. This study shows HFPV is an effective salvage therapy for ARDS patients refractory to standard mechanical ventilation.

Keywords:
ARDShigh-frequency percussive ventilationmechanical ventilation

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