Related Experiment Video
Updated: Aug 5, 2026

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
Published on: August 26, 2014
The effect of neuroimmune signalling on drug addiction
Qianzhao Chen1, Haoran Chi1, Shuang Liu1
1Department of Pharmacy, Liang jiang Hospital of Chongqing Medical University, Chongqing, China.
Abstract:
The relationship between neuroimmune processes and drug addiction is currently unclear, although long-term drug use affects neuroimmune signalling. Currently, how neuroinflammation and neuroimmune signalling are linked to addiction is unclear. Therefore, the purpose of this review is to elucidate the roles of neuroimmune signalling, its interaction with neuroinflammation resulting from long-term drug use, and the possible influence of this interaction on the use of pharmacotherapeutic approaches for treating drug addiction. In this review, we address the roles of chemokines and cytokines in the rewarding and reinforcing effects of psychostimulants. Additionally, we provide an overview of novel anti-inflammatory therapeutic strategies that differ from conventional strategies by focusing on cytokines and chemokines. Understanding the role that neuroimmune signalling plays in drug addiction may help researchers develop innovative strategies for addressing this serious social problem.
Related Concept Videos
Neurochemical Transmission: Sites of Drug Action
Drug Abuse and Addiction: Pharmacological Phenomena
Drugs Affecting Neurotransmitter Release or Uptake
Drugs Affecting Neurotransmitter Synthesis
CNS Depressants: Alcohol and Nicotine
Drug Dependence

