Related Experiment Video
Updated: Aug 5, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
A Rare Case of Scrofuloderma Presenting as Recurrent Tuberculosis in a Young Patient
Yoshihiro Okada1, Asuka Okada1,2, Shin Miyagawa1
1Department of Respiratory Medicine Osaka Saiseikai Suita Hospital Suita Osaka Japan.
Tuberculosis (TB) can recur and present as scroderma, a skin ulcer, due to the contiguous spread from underlying chest abscesses. Prompt diagnosis of skin ulcers involves histopathological and bacteriological assessments.
Area of Science:
- Infectious Diseases
- Dermatology
- Pulmonology
Background:
- A 23-year-old Indonesian man with a history of pulmonary tuberculosis presented with a chest wall skin ulcer.
- Recurrent tuberculosis can arise from residual strains or reinfection.
Purpose of the Study:
- To report a case of recurrent tuberculosis manifesting as scrofuloderma.
- To highlight the diagnostic approach for unusual presentations of tuberculosis.
Main Methods:
- Clinical examination, chest ultrasonography, and computed tomography were performed.
- Histopathological examination of a skin biopsy and polymerase chain reaction (PCR) for Mycobacterium tuberculosis were conducted on ulcer exudate.
Main Results:
- Imaging revealed intercostal abscesses and pleural thickening with calcification.
- Histology and PCR confirmed Mycobacterium tuberculosis in the skin ulcer and exudate.
- The patient was diagnosed with scrofuloderma and multiple intercostal abscesses secondary to recurrent tuberculosis.
Conclusions:
- Recurrent tuberculosis can present as scrofuloderma via contiguous spread from underlying abscesses.
- Thorough histopathological and bacteriological assessments are crucial for diagnosing skin ulcers of unclear etiology.
- This case underscores the importance of considering tuberculosis in patients with atypical skin manifestations, especially those with a prior history.
Related Concept Videos
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Tuberculosis
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...