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Extrapulmonary Tuberculosis with Seminal Vesicle Involvement in an Immunocompetent Patient
Padma Lahari Bayya1, Mohini Singh, S R Ramakrishnan
1Department of Internal Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Annals of African Medicine
|July 28, 2026
Summary
This case study emphasizes diagnosing extrapulmonary tuberculosis (EPTB) in immunocompetent individuals. Early recognition of EPTB is crucial, even without lung involvement, for timely treatment and better patient outcomes.
Area of Science:
- Medicine
- Infectious Diseases
- Neurology
Background:
- Extrapulmonary tuberculosis (EPTB) poses diagnostic challenges due to multi-organ involvement.
- Neurological symptoms and sterile pyuria can be indicators of EPTB.
Purpose of the Study:
- To report a unique case of EPTB in an immunocompetent patient.
- To highlight the diagnostic difficulties and importance of considering EPTB in non-typical presentations.
Main Methods:
- Case report of a 54-year-old male with prolonged fever and seizure.
- Diagnostic workup included neuroimaging, histopathology, and microbiological analysis.
- Treatment involved antitubercular therapy, anti-convulsants, and steroids.
Main Results:
- Neuroimaging revealed ring-enhancing lesions consistent with tuberculomas.
- Seminal vesicle abscess and cervical lymphadenitis were identified.
- Histopathology and cultures confirmed tuberculosis.
Conclusions:
- EPTB should be considered in immunocompetent patients presenting with neurological symptoms and sterile pyuria, even without pulmonary disease.
- Multisystemic involvement necessitates a high index of suspicion for EPTB.
- Prompt diagnosis and treatment are essential for managing EPTB.
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