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Postmastectomy Radiotherapy in Immediate Autologous Breast Reconstruction: A Patient-Reported and Clinical Outcomes
Li Yenn Yong1, Mohammed Herieka1, Rini Vyas1
1From the Departments of Plastic Surgery.
Plastic and Reconstructive Surgery
|July 28, 2026
Summary
Immediate breast reconstruction using deep inferior epigastric artery (DIEP) flaps is safe after postmastectomy radiotherapy (PMRT). Outcomes were comparable, though slight decreases in breast satisfaction were noted in the PMRT group.
Area of Science:
- Oncology
- Plastic Surgery
- Reconstructive Surgery
Background:
- Radiotherapy is a standard breast cancer treatment, posing challenges for immediate breast reconstruction.
- Deep inferior epigastric artery (DIEP) flap reconstruction is a common autologous option.
Purpose of the Study:
- To compare complications and aesthetic/patient-reported outcomes of immediate DIEP flap breast reconstruction with and without postmastectomy radiotherapy (PMRT).
Main Methods:
- Prospective data collection over 3 years for patients undergoing mastectomy and immediate DIEP flap reconstruction.
- Assessment of surgical complications, aesthetic outcomes (surgeon-reported), and patient-reported outcomes (BREAST-Q).
Main Results:
- 108 patients (134 reconstructions) were analyzed; 53 received PMRT.
- Surgical complication rates were similar between groups.
- Patient satisfaction was comparable, with a slight decrease in breast satisfaction in the PMRT group (84% vs. 76%).
Conclusions:
- Immediate autologous breast reconstruction with DIEP flaps is safe following PMRT.
- Satisfactory aesthetic and patient-reported outcomes can be achieved even with PMRT.
