Electronic Cigarettes: A Comprehensive Review for Primary Care Providers
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Updated: Aug 5, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Marilyn Kimbrough1, Elizabeth Cius2
1Department of Pediatrics, Naval Medical Center San Diego, San Diego, CA, USA.
Abstract:
Elecronic cigarettes (e-cigarettes), initially marketed as a safer smoking alternative, have gained widespread use, especially among adolescents and young adults who did not previously smoke. While our understanding of long-term risks is still emerging, vaping carries significant concerns for adolescents, including nicotine dependence, increased risk of substance use disorders and mood disorders, and potential cardiovascular and pulmonary harm. Primary care clinicians should routinely screen for e-cigarette use in adolescents and young adults and counsel patients on associated risks, emphasizing that safer doesn't mean safe.
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