Hostile Fields and Limited Options: Autologous Peritoneal Grafting as a Salvage Strategy for Complex Perineal Defects
Charalampos Theocharopoulos1, Dimitrios N Varvoglis1, Ioannis A Ziogas1
1Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
The American Surgeon
|July 29, 2026
Summary
This study introduces a novel, low-morbidity salvage technique for large pelvic floor defects. It utilizes an autologous peritoneal graft and vacuum-assisted closure for complex perineal reconstruction, offering a mesh-free solution.
Area of Science:
- Surgical Reconstruction
- Pelvic Floor Surgery
- Wound Management
Background:
- Pelvic floor defects can arise after malignancy or infection surgery.
- Reconstruction is challenging in patients with radiation, comorbidities, or malnutrition.
- Conventional methods may fail in complex, contaminated perineal cases.
Purpose of the Study:
- To present a salvage approach for large, contaminated perineal defects.
- To describe the use of an autologous peritoneal graft as a pelvic partition.
- To evaluate vacuum-assisted closure in conjunction with this technique.
Main Methods:
- Harvesting an autologous peritoneal graft from parietal peritoneum and hernia sac.
- Suturing the graft to partition the pelvic inlet from the peritoneal cavity.
- Applying vacuum-assisted closure (VAC) from postoperative day 4 to 43.
Main Results:
- The technique successfully partitioned the pelvic cavity.
- VAC therapy significantly reduced the wound size.
- The approach provided a tension-free, mesh-free reconstruction.
Conclusions:
- Autologous peritoneal grafting followed by VAC is a viable salvage option for complex perineal defects.
- This method is particularly useful in irradiated or contaminated surgical fields.
- It offers a mesh-free alternative when standard reconstructions are not feasible.


