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DBT reconstruction based on 3D coordinate transformation of multi-angle projections
1Nanjing University of Posts and Telecommunications, College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing 210023, China.
Journal of X-Ray Science and Technology
|July 29, 2026
Summary
A new 3D coordinate transformation method for Digital Breast Tomosynthesis (DBT) reconstruction significantly reduces geometric distortion. This improves image quality and lesion detection, enhancing diagnostic accuracy for breast disease.
Area of Science:
- Medical Imaging
- Radiology
- Image Reconstruction
Background:
- Digital Breast Tomosynthesis (DBT) is an advanced imaging technique for breast disease diagnosis.
- DBT reconstructs 3D images, reducing tissue overlap and improving lesion detection.
- Conventional DBT reconstruction methods suffer from vertical geometric distortion, blurring subtle lesions.
Purpose of the Study:
- To develop and evaluate a novel DBT reconstruction method addressing geometric distortion.
- To improve image quality and lesion visualization in DBT.
Main Methods:
- A five-step pipeline involving preprocessing, 3D coordinate transformation, interpolation, weighting, and reconstruction.
- 3D coordinate transformation corrects for geometric distortion based on acquisition parameters.
- Angular weighting balances sampling density across projections.
Main Results:
- The 3D coordinate transformation method significantly reduced geometric distortion.
- Improvements observed include increased PSNR (1.19 dB) and reduced SD for FBP reconstruction.
- CNR improved by approximately 15.4% for MLEM reconstruction.
- Clinical data confirmed enhanced lesion differentiation.
Conclusions:
- The proposed 3D coordinate transformation-based DBT reconstruction enhances image quality.
- This method shows potential for broader clinical applications in breast imaging.
- Improved accuracy in differentiating lesions from background tissue.
