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Published on: April 7, 2015

Clostridium perfringens Infective Endocarditis: Revisiting a Forgotten Pathogen

Jake Rubin1, Scott Eisenberg2, Matthew Gold3

  • 1Emory University School of Medicine, Atlanta, Georgia, USA.

JACC. Case Reports
|July 29, 2026
PubMed
Abstract

Insights

Clostridium perfringens is a rare cause of infective endocarditis (IE). Advanced imaging like cardiac CT is crucial for detecting vegetations in complex congenital heart disease, guiding successful non-surgical treatment.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Clostridium perfringens is an uncommon pathogen causing infective endocarditis (IE).
  • Limited case reports exist for IE caused by this bacterium.
  • Complex congenital heart disease (CHD) presents unique challenges in IE management.
Keywords:
computed tomographycongenital heart defectdouble outlet right ventricleechocardiographyendocarditispulmonic valveright ventriclevalve repairventricular septal defect

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