Related Experiment Video
Updated: Aug 5, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
Mutism in a patient with Gilles de la Tourette syndrome
Mafalda Matias1,2, Teresa Barata Silvério1, Ana Filipa Lopes3
1Department of Pediatrics, Neuropediatrics Unit, Torrado da Silva Child Development Center, Hospital Garcia de Orta, Unidade Local de Saúde Almada-Seixal, Almada, Portugal.
Abstract:
A 5-year-old boy with a prior history of stuttering presented to the neuropaediatrics clinic with prominent motor and vocal tics, including intrusive syllables, was diagnosed with Gilles de la Tourette syndrome (GTS). One month later, near-complete mutism developed acutely, which improved progressively after treatment with risperidone. During the follow-up, motor and vocal tics fluctuated concurrently, but without clear-cut mutism. GTS encompasses a range of vocal tics, including vocal-blocking phenomena, which made us postulate that this case may represent an extreme expression of vocal blocking tics.
Related Concept Videos
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Alterations in Muscle Tone lll
Myasthenia Gravis ll: Pathophysiology
Tonsillitis II: Management
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Alterations in Muscle Tone ll
