Related Experiment Video
Updated: Aug 5, 2026

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil
Published on: January 4, 2014
[Clinical Research Action Plan in Brazil: analysis of its implementation process and main results, 2018-2025]
Giovanny Vinícius Araújo de França1, Evandro de Oliveira Lupatini1, Michelle Zanon Pereira1
1Secretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.
None:
This study evaluated the Clinical Research Action Plan in Brazil (PAPCB, acronym in Portuguese), established in 2018 by the Brazilian Ministry of Health. This ex post public policy evaluation study was based on documentary analysis for the 2018-2025 period. The six strategic axes of the PAPCB were considered: ethical regulation, sanitary regulation, scientific and technological promotion, training in clinical research, the Clinical Research National Network (RNPC, acronym in Portuguese), and knowledge management. The results showed significant advances in scientific promotion and professional training, with broad execution of the planned actions. The training of more than 45,000 professionals stands out in the training axis. The RNPC underwent restructuring, giving rise to the Brazilian Network of Clinical Research (RBPClin, acronym in Portuguese). However, structural challenges persist, such as the need to modernize Plataforma Brasil, improve knowledge management, and strengthen network collaboration. This study recommends the review and update of the PAPCB, incorporating strategies to overcome these gaps to consolidate the Brazilian scientific, technological, and institutional capacity in clinical research.
Related Concept Videos
Clinical Trials: Overview
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Drug Control Governance: Regulatory Bodies and Their Impact
Clinical Trials
There are four phases in a clinical trial. A phase one...
Preclinical Development: Overview
Drug Regulation
