Related Experiment Video
Updated: Aug 5, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Agreement between structural parameters provided by the swept-source OCT and Laguna ONhE
Gilvan Vilarinho da Silva Filho1, Gustavo Coelho Caiado1, Olívia Moura de Paula Ricardo2
1Glaucoma Service, Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Purpose:
To evaluate the agreement between optic nerve head structural parameters obtained using swept-source optical coherence tomography and the Laguna ONhE software.
Methods:
This retrospective cross-sectional study included 353 eyes from healthy individuals, glaucoma suspects, ocular hypertensive patients, and patients with glaucoma. Optic nerve head parameters-including disc area, vertical and area cup-to-disc ratios, and rim volume-were measured using swept-source optical coherence tomography and Laguna ONhE. Agreement between methods was assessed using Bland-Altman analysis. A regression-based calibration model was developed for disc area measurements.
Results:
Laguna ONhE systematically underestimated disc area (p < 0.001) and cup-to-disc ratios (p<0.001) and overestimated rim volume (p=0.0002) compared with swept-source optical coherence tomography. After applying the calibration equation for disc area, agreement improved substantially, with no statistically significant bias (p=0.3).
Conclusion:
Laguna ONhE provides structural estimates comparable with those obtained with swept-source optical coherence tomography after calibration, suggesting it may serve as a practical and cost-effective alternative for glaucoma evaluation.
Related Concept Videos
Time and frequency -Domain Interpretation of Phase-lag Control
Phase-lag controllers do not place a pole at zero, but instead influence the steady-state error by amplifying any finite,...
Oscillations In An LC Circuit
Sinusoidal Sources
In homes, the power supplies use sinusoidal sources to provide electricity. These sources generate a voltage that varies sinusoidally...
Laminar Flow
Boundary Layer Characteristics
Eulerian and Lagrangian Flow Descriptions
The Eulerian method focuses on fixed points in space where fluid properties, such as velocity, pressure, and temperature, are observed as the fluid moves between these...

