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Infantile Basal Ganglia Infarct due to Mineralizing Angiopathy: A Case Report
Ashley Strube1, Callie Olson2, Gokhan Olgun3,4
1Pediatrics Residency Program, University of South Dakota Sanford School of Medicine.
Insights
Mineralizing angiopathy, a rare condition, can mimic acute ischemic stroke (AIS) in infants. Microcalcifications in lenticulostriate arteries, not hemorrhages, are key neuroradiologic findings.
Area of Science:
- Pediatric Neurology
- Neuroradiology
- Rare Diseases
Background:
- Acute onset hemiparesis in infants can be a diagnostic challenge.
- Initial imaging may suggest acute ischemic stroke (AIS), necessitating further investigation.
- Mineralizing angiopathy is a rare condition with limited documented cases.
Abstract:
An 11-month-old female infant without any significant past medical history presented to an outside facility emergency department due to acute onset hemiparesis. Initial head CT imaging was negative for acute ischemic stroke (AIS). The patient was transferred to our children's hospital for further evaluation and management. Previous head imaging was read again by a pediatric radiologist who reported AIS of the basal ganglia with what was thought to be punctate hemorrhages surrounding the penumbra. After further MRI imaging studies were completed, the area initially believed to be punctate hemorrhages was identified instead as microcalcifications of the lenticulostriate arteries, and a diagnosis of mineralizing angiopathy was made. Given this entity's scarcity of documented cases, it is important for physicians to be aware of the diagnosis, as well as the associated neuroradiologic findings.
