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Development of an In Vitro Permeation Test Framework For Naloxone Hydrochloride Intranasal Spray: Establishing IVIVR

Tasmin Ara Sultana1, Manar Al-Ghabeish2, Steven Chopski3

  • 1Division of Pharmaceutical Quality Research V, Office of Pharmaceutical Quality Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA.

Pharmaceutical Research
|July 29, 2026
PubMed
Abstract

Keywords:
in vitro permeation testin vitro–in vivo extrapolationin vitro–in vivo relationshipbioequivalencenaloxone

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