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Published on: April 23, 2021
Granular cell tumor mimicking breast carcinoma in a 49-year-old female: a case report
Fadoua El Mansouri1, Khadija Bichri1, Zakaria Hafiani1,2
1Immunopathology-Immunotherapy-Immunomonitoring Laboratory, Faculty of Medicine, Mohammed VI University of Sciences and Health (UM6SS), Casablanca, Morocco.
Abstract:
Abrikossoff entities, also known as granular cell tumors (GCTs), are categorized as rare benign soft-tissue tumors of Schwann cell origin. The most common site of predilection is the oral cavity, followed by the skin, breast, digestive tract, and tracheobronchial tree; the least common location is the central nervous system. They are benign growths associated with a good prognosis, with surgical resection being their standard treatment. However, sometimes, they become malignant. They typically manifest as solitary tumors; hence, multiple lesions are rare. Here, we report a 49-year-old woman with a palpable and painful mass in her right breast. While the clinical and radiological features favored a diagnosis of epidermoid cyst, immunohistochemistry confirmed an Abrikossoff tumor. No recurrence of the GCT was assessed during the control.

