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Updated: Aug 5, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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Enantioselective Synthesis of cis-Hydroisoquinolines via Cross-[4 + 2] Cycloadditions of 2‑Pyrones and

Jun-Xiong He1, Qi-Tao Lu1, Kui Tan1

  • 1Department of Chemistry, Research Center for Molecular Recognition and Synthesis, State Key Laboratory of Green Chemical Synthesis and Conversion, Fudan University, 220 Handan Rd., Shanghai 200433, China.

JACS Au
|July 30, 2026
PubMed

Keywords:
2-pyronesasymmetric catalysiscis-hydroisoquinolinescross-[4 + 2] cycloadditionsperiselectivity

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