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Updated: Aug 5, 2026
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Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
Coronary Perforation During Excimer Laser Angioplasty in a Patient With Prior Thoracic Radiotherapy
Francesco Maria Sparasci1,2, Alessandro Cafaro2, Dionigi Fischetti2
1Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Summary
Excimer laser coronary angioplasty (ELCA) for calcified lesions can cause coronary perforation, especially after radiation therapy. This case highlights the risks of plaque modification in complex coronary artery disease.
Area of Science:
- Interventional Cardiology
- Cardiovascular Imaging
- Vascular Biology
Background:
- Managing heavily calcified coronary lesions is difficult.
- Excimer laser coronary angioplasty (ELCA) is a useful adjunctive therapy with low risk of no-reflow.
- Radiation therapy can affect vessel wall properties.
Related Concept Videos
01:28Esophageal Perforation-II: Clinical Manifestations and Management
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
01:22Esophageal Perforation-I: Introduction
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...