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Updated: Aug 5, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Published on: October 28, 2020

This ECG Does Not Fit: Rethinking Left Ventricular Hypertrophy

Carlotta Perini Schweiger1, Giuseppe Allocca2, Giorgia Gugelmo3

  • 1Department of Cardiac-thoracic-vascular sciences and Public health, University of Padua, Padua, Italy.

JACC. Case Reports
|July 30, 2026
PubMed

Insights

Late-onset Anderson-Fabry disease (AFD) is often missed in older adults with comorbidities. Electrocardiogram (ECG) changes can be key clues for diagnosing this rare cause of left ventricular hypertrophy (LVH).

Area of Science:

  • Cardiology
  • Genetics
  • Rare Diseases

Background:

  • Anderson-Fabry disease (AFD) is a rare genetic disorder.
  • It can present as left ventricular hypertrophy (LVH), often challenging to diagnose.
  • Comorbidities in older patients can further complicate AFD diagnosis.
Abstract

Keywords:
cardiac magnetic resonancecardiomyopathyelectrocardiogram

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